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A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Subjects with De Novo Coronary Artery Lesions - SPIRIT IV

To evaluate the safety and efficacy of the XIENCE V Everolimus Eluting Coronary Stent System (XIENCE V) for the treatment of up to three de novo native coronary artery lesions, maximum of two lesions per epicardial vessel.


Biorepository for the Preservation and Study of Human Carcinogenesis

To provide a reliable resource of specimens for research in the realm of oncological and hematological diseases. The broader aim is to allow physicians, academicians, and corporate researchers who are dedicated to the study of cancer and blood problems to more quickly find better treatments for diseases that are not currently considered curable.


Induction of Donor Specific Tolerance in Recipients of Cardiac Allografts by Donor Bone Marrow Cell Infusion

The purpose of this study is to administer donor bone marrow cells to heart transplant recipients in an attempt to induce donor specific tolerance enabling discontinuation or decrease in the doses of immunosuppressive therapy.


Induction of Donor Specific Tolerance in Recipients of Kidney Allografts by Donor Bone Marrow Cell Infusion

To determine whether the administration of donor bone marrow, enriched for hematopoietic stem cells (HSC) and graft facilitating cells (FC) and depleted of GVHD-producing cells, will induce tolerance to a donor-specific renal allograft and substantially reduce or eliminate the requirement for chronic nonspecific immunosuppressive agents within 12 months following transplantation.


Induction of Donor Specific Tolerance in Recipients of Live Donor Kidney Allografts by Donor Stem Cell Infusion

To determine whether the administration of mobilized peripheral blood or bone marrow, enriched for HSC and graft FC and depleted of GVHD-producing cells, will induce tolerance to a donor-specific renal allograft and substantially reduce or eliminate the requirement for chronic nonspecific immunosuppressive agents within 12 months following transplantation.


MENTOR Silicone Gel-Filled Mammary Prosthesis Adjunct Clinical Study

The purpose of this study is to collect safety data asssociated with the implantation of gel-filled mammary prostheses.


Molecular Epidemology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men

The purpose of this study is to determine why women are more likely to be diagnosed with certain types of lung cancer than men are, and to see if factors other than smoking may put women at higher risk of lung cancer than men.


Randomized Trial of Mediastinal Lymph Node Sampling vs. Complete Lymphadenectomy During Pulmonary Resection in the Patient with N0 or N1 (less than hilar) Non-small Cell Carcinoma

To evaluate whether complete mediastinal lymph node dissection results in better overall survival when compared to mediastinal lymph node sampling in the patient undergoing resection for N0 or non-hilar N1 NSCLC.


Tissue and Blood Procurement for Research Purposes Only

To establish a bank of blood samples, serum, and tissue for various solid tumors to allow for future research testing.


Use of Proteomic Analysis of Serum Samples for Detection of Non-Small Cell Lung Cancer - ACOSOG Z4031

To determine prospectively whetehr the serum proteomic profile can predict the presence of primary NSCLC in patients with suspicious lung lesions who are candidates for lung resection.